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doi: 10.1161/ATVBAHA.120.315267 204 NotzQ.HerrmannJ.SchlesingerT.HelmerP.SudoweS.SunQ.et al

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For example, it has been suggested that rapid metabolism for cytochrome P450 2D6 (CYP2D6) and N -acetyl transferase 2 (NAT2) enzymes may elevate the risk of MCS and that the genotypic frequencies of CYP superfamily, UDP-glucuronosyltransferase (UGT), and glutathione S-transferases mu, theta, and pi (GSTM, GSTT, and GSTP) in MCS patients are similar to those in the control population [12, 23]